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Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome.
A family of ATPases resides within the regulatory particle of the proteasome. These proteins (Rpt1-Rpt6) have been proposed to mediate substrate unfolding, which may be required for translocation of substrates through the channel that leads from the regulatory particle into the proteolytic core part...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170820/ https://ncbi.nlm.nih.gov/pubmed/9724628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.17.4909 |
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