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The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme.

Seven of the approximately 40 subunits of the mammalian respiratory NADH dehydrogenase (Complex I) are encoded in mitochondrial DNA (mtDNA). Their function is almost completely unknown. In this work, a novel selection scheme has led to the isolation of a mouse A9 cell derivative defective in NADH de...

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Bibliographische Detailangaben
Hauptverfasser: Bai, Y, Attardi, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170814/
https://ncbi.nlm.nih.gov/pubmed/9707444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.16.4848
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