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Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase.

The mitochondrial NADH dehydrogenase (complex I) in mammalian cells is a multimeric enzyme consisting of approximately 40 subunits, 7 of which are encoded in mitochondrial DNA (mtDNA). Very little is known about the function of these mtDNA-encoded subunits. In this paper, we describe the efficient i...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Hofhaus, G, Attardi, G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823960/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.964
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