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E1A directly binds and regulates the P/CAF acetyltransferase.
The P/CAF protein has intrinsic histone acetyltransferase (HAT) activity and is capable of binding the transcriptional co-activator CBP. Here we show that P/CAF can regulate transcription and that this function is independent of its binding to CBP. The HAT domain of P/CAF has transcriptional activat...
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| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1998
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170778/ https://ncbi.nlm.nih.gov/pubmed/9687513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.15.4469 |
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