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E1A directly binds and regulates the P/CAF acetyltransferase.

The P/CAF protein has intrinsic histone acetyltransferase (HAT) activity and is capable of binding the transcriptional co-activator CBP. Here we show that P/CAF can regulate transcription and that this function is independent of its binding to CBP. The HAT domain of P/CAF has transcriptional activat...

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Detalhes bibliográficos
Main Authors: Reid, J L, Bannister, A J, Zegerman, P, Martínez-Balbás, M A, Kouzarides, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170778/
https://ncbi.nlm.nih.gov/pubmed/9687513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.15.4469
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