Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.

Heterotrimeric G proteins of the Gq class have been implicated in signaling pathways regulating cardiac growth under physiological and pathological conditions. Knockout mice carrying inactivating mutations in both of the widely expressed G alpha q class genes, G alpha q and G alpha 11, demonstrate t...

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Bibliographic Details
Main Authors: Offermanns, S, Zhao, L P, Gohla, A, Sarosi, I, Simon, M I, Wilkie, T M
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170764/
https://ncbi.nlm.nih.gov/pubmed/9687499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.15.4304
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