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Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin.

The C-terminal domain NC1 of mouse collagen XVIII (38 kDa) and the shorter mouse and human endostatins (22 kDa) were prepared in recombinant form from transfected mammalian cells. The NC1 domain aggregated non-covalently into a globular trimer which was partially cleaved by endogenous proteolysis in...

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Autors principals: Sasaki, T, Fukai, N, Mann, K, Göhring, W, Olsen, B R, Timpl, R
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170758/
https://ncbi.nlm.nih.gov/pubmed/9687493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.15.4249
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