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Secreted cathepsin L generates endostatin from collagen XVIII
Endostatin, an inhibitor of angiogenesis and tumor growth, was identified originally in conditioned media of murine hemangioendothelioma (EOMA) cells. N–terminal amino acid sequencing demonstrated that it corresponds to a fragment of basement membrane collagen XVIII. Here we report that cathepsin L...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305660/ https://ncbi.nlm.nih.gov/pubmed/10716919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.6.1187 |
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