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MPF localization is controlled by nuclear export.

In eukaryotes, mitosis is initiated by M phase promoting factor (MPF), composed of B-type cyclins and their partner protein kinase, CDK1. In animal cells, MPF is cytoplasmic in interphase and is translocated into the nucleus after mitosis has begun, after which it associates with the mitotic apparat...

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Main Authors: Hagting, A, Karlsson, C, Clute, P, Jackman, M, Pines, J
Formato: Artigo
Idioma:Inglês
Publicado: 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170745/
https://ncbi.nlm.nih.gov/pubmed/9670027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.4127
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