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MPF localization is controlled by nuclear export.

In eukaryotes, mitosis is initiated by M phase promoting factor (MPF), composed of B-type cyclins and their partner protein kinase, CDK1. In animal cells, MPF is cytoplasmic in interphase and is translocated into the nucleus after mitosis has begun, after which it associates with the mitotic apparat...

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Autors principals: Hagting, A, Karlsson, C, Clute, P, Jackman, M, Pines, J
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170745/
https://ncbi.nlm.nih.gov/pubmed/9670027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.4127
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