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MPF localization is controlled by nuclear export.
In eukaryotes, mitosis is initiated by M phase promoting factor (MPF), composed of B-type cyclins and their partner protein kinase, CDK1. In animal cells, MPF is cytoplasmic in interphase and is translocated into the nucleus after mitosis has begun, after which it associates with the mitotic apparat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170745/ https://ncbi.nlm.nih.gov/pubmed/9670027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.4127 |
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