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Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity.
Tissues with the highest rates of proliferation typically exhibit the highest frequencies of apoptosis, but the mechanisms that coordinate these processes are largely unknown. The homeodomain protein Gax is down-regulated when quiescent cells are stimulated to proliferate, and constitutive Gax expre...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170694/ https://ncbi.nlm.nih.gov/pubmed/9649428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.13.3576 |
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