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How p53 binds DNA as a tetramer.
The p53 tumor suppressor protein is a tetramer that binds sequence-specifically to a DNA consensus sequence consisting of two consecutive half-sites, with each half-site being formed by two head-to-head quarter-sites (--><-- --><--). Each p53 subunit binds to one quarter-site, resulting...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170672/ https://ncbi.nlm.nih.gov/pubmed/9628871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.12.3342 |
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