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How p53 binds DNA as a tetramer.

The p53 tumor suppressor protein is a tetramer that binds sequence-specifically to a DNA consensus sequence consisting of two consecutive half-sites, with each half-site being formed by two head-to-head quarter-sites (--><-- --><--). Each p53 subunit binds to one quarter-site, resulting...

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Bibliografiske detaljer
Main Authors: McLure, K G, Lee, P W
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170672/
https://ncbi.nlm.nih.gov/pubmed/9628871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.12.3342
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