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Antagonism in the human mineralocorticoid receptor.
Key residues of the human mineralocorticoid receptor (hMR) involved in the recognition of agonist and antagonist ligands were identified by alanine-scanning mutagenesis based on a homology model of the hMR ligand-binding domain. They were tested for their transactivation capacity and ability to bind...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170670/ https://ncbi.nlm.nih.gov/pubmed/9628869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.12.3317 |
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