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Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation.
The AML1 transcription factor and the transcriptional coactivators p300 and CBP are the targets of chromosome translocations associated with acute myeloid leukemia and myelodysplastic syndrome. In the t(8;21) translocation, the AML1 (CBFA2/PEBP2alphaB) gene becomes fused to the MTG8 (ETO) gene. We p...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170639/ https://ncbi.nlm.nih.gov/pubmed/9606182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.11.2994 |
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