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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function.

Vps4p is an AAA-type ATPase required for efficient transport of biosynthetic and endocytic cargo from an endosome to the lysosome-like vacuole of Saccharomyces cerevisiae. Vps4p mutants that do not bind ATP or are defective in ATP hydrolysis were characterized both in vivo and in vitro. The nucleoti...

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Autors principals: Babst, M, Wendland, B, Estepa, E J, Emr, S D
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170638/
https://ncbi.nlm.nih.gov/pubmed/9606181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.11.2982
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