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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function.
Vps4p is an AAA-type ATPase required for efficient transport of biosynthetic and endocytic cargo from an endosome to the lysosome-like vacuole of Saccharomyces cerevisiae. Vps4p mutants that do not bind ATP or are defective in ATP hydrolysis were characterized both in vivo and in vitro. The nucleoti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1998
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170638/ https://ncbi.nlm.nih.gov/pubmed/9606181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.11.2982 |
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