Nalaganje...

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha.

In extracts of human cells, base-base mismatches and small insertion/deletion loops are bound primarily by hMutSalpha, a heterodimer of hMSH2 and hMSH6 (also known as GTBP or p160). Recombinant hMutSalpha bound a G/T mismatch-containing oligonucleotide with an apparent dissociation constant Kd = 2.6...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Iaccarino, I, Marra, G, Palombo, F, Jiricny, J
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170608/
https://ncbi.nlm.nih.gov/pubmed/9564049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.9.2677
Oznake: Označite
Brez oznak, prvi označite!