Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Apoptosis signal-regulating kinase (ASK) 1 was recently identified as a mitogen-activated protein (MAP) kinase kinase kinase which activates the c-Jun N-terminal kinase (JNK) and p38 MAP kinase pathways and is required for tumor necrosis factor (TNF)-alpha-induced apoptosis; however, the mechanism r...

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Main Authors: Saitoh, M, Nishitoh, H, Fujii, M, Takeda, K, Tobiume, K, Sawada, Y, Kawabata, M, Miyazono, K, Ichijo, H
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170601/
https://ncbi.nlm.nih.gov/pubmed/9564042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.9.2596
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