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Cell wall integrity modulates RHO1 activity via the exchange factor ROM2.
The essential phosphatidylinositol kinase homologue TOR2 of Saccharomyces cerevisiae controls the actin cytoskeleton by activating a GTPase switch consisting of RHO1 (GTPase), ROM2 (GEF) and SAC7 (GAP). We have identified two mutations, rot1-1 and rot2-1, that suppress the loss of TOR2 and are synth...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170568/ https://ncbi.nlm.nih.gov/pubmed/9545237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.8.2235 |
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