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Transformation abrogates an early G1-phase arrest point required for specification of the Chinese hamster DHFR replication origin.
The origin decision point (ODP) was originally identified as a distinct point during G1-phase when Chinese hamster ovary (CHO) cell nuclei experience a transition that is required for specific recognition of the dihydrofolate reductase (DHFR) origin locus by Xenopus egg extracts. Passage of cells th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170528/ https://ncbi.nlm.nih.gov/pubmed/9501102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.6.1810 |
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