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The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation.

The Ras GTPase plays an essential role in many cellular signal transduction events. Activation of the mitogen activated protein (MAP) kinase is a primary consequence of Ras activation and plays a key role in mediating Ras signal transduction. A novel kinase, KSR, has recently been functionally isola...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sugimoto, T, Stewart, S, Han, M, Guan, K L
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170519/
https://ncbi.nlm.nih.gov/pubmed/9501093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.6.1717
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