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Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases.
MutS, MutL and MutH are the three essential proteins for initiation of methyl-directed DNA mismatch repair to correct mistakes made during DNA replication in Escherichia coli. MutH cleaves a newly synthesized and unmethylated daughter strand 5' to the sequence d(GATC) in a hemi-methylated duple...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170500/ https://ncbi.nlm.nih.gov/pubmed/9482749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.5.1526 |
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