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epsilon-COP is a structural component of coatomer that functions to stabilize alpha-COP.
We isolated a novel yeast alpha-COP mutant, ret1-3, in which alpha-COP is degraded after cells are shifted to a restrictive temperature. ret1-3 cells cease growth at 28 degrees C and accumulate the ER precursor of carboxypeptidase Y (p1 CPY). In a screen for high copy suppressors of these defects, w...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170448/ https://ncbi.nlm.nih.gov/pubmed/9463377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.985 |
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