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epsilon-COP is a structural component of coatomer that functions to stabilize alpha-COP.

We isolated a novel yeast alpha-COP mutant, ret1-3, in which alpha-COP is degraded after cells are shifted to a restrictive temperature. ret1-3 cells cease growth at 28 degrees C and accumulate the ER precursor of carboxypeptidase Y (p1 CPY). In a screen for high copy suppressors of these defects, w...

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Autors principals: Duden, R, Kajikawa, L, Wuestehube, L, Schekman, R
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170448/
https://ncbi.nlm.nih.gov/pubmed/9463377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.985
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