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Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling.
Raf-1 kinase is a central regulator of mitogenic signal pathways, whereas its general role in signal transduction of tumour necrosis factor (TNF) is less well defined. We have investigated mechanisms of Raf-1 regulation by TNF and its messenger ceramide in cell-free assays, insect and mammalian cell...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
1998
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170422/ https://ncbi.nlm.nih.gov/pubmed/9450998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.3.732 |
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