An actively retrotransposing, novel subfamily of mouse L1 elements.

Retrotransposition of LINEs and other retroelements increases repetition in mammalian genomes and can cause deleterious mutations. Recent insertions of two full-length L1s, L1spa and L1Orl, caused the disease phenotypes of the spastic and Orleans reeler mice respectively. Here we show that these two...

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Библиографические подробности
Главные авторы: Naas, T P, DeBerardinis, R J, Moran, J V, Ostertag, E M, Kingsmore, S F, Seldin, M F, Hayashizaki, Y, Martin, S L, Kazazian, H H
Формат: Artigo
Язык:Inglês
Опубликовано: 1998
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170408/
https://ncbi.nlm.nih.gov/pubmed/9430649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.2.590
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