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An actively retrotransposing, novel subfamily of mouse L1 elements.
Retrotransposition of LINEs and other retroelements increases repetition in mammalian genomes and can cause deleterious mutations. Recent insertions of two full-length L1s, L1spa and L1Orl, caused the disease phenotypes of the spastic and Orleans reeler mice respectively. Here we show that these two...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1998
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170408/ https://ncbi.nlm.nih.gov/pubmed/9430649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.2.590 |
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