Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome.

The transcription factor HNF3 and linker histones H1 and H5 possess winged-helix DNA-binding domains, yet HNF3 and other fork head-related proteins activate genes during development whereas linker histones compact DNA in chromatin and repress gene expression. We compared how the two classes of facto...

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Main Authors: Cirillo, L A, McPherson, C E, Bossard, P, Stevens, K, Cherian, S, Shim, E Y, Clark, K L, Burley, S K, Zaret, K S
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170375/
https://ncbi.nlm.nih.gov/pubmed/9427758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.1.244
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