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Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1.

In response to interferon-gamma (IFN-gamma), Stat1 is tyrosine phosphorylated and translocates to the nucleus where it activates transcription. In this study, we identified factors which mediate the nuclear import of Stat1. Tyrosine-phosphorylated Stat1 associated with the beta subunit (a 97 kDa com...

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Autors principals: Sekimoto, T, Imamoto, N, Nakajima, K, Hirano, T, Yoneda, Y
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170309/
https://ncbi.nlm.nih.gov/pubmed/9384585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.23.7067
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