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Stimulation of gene induction and cell growth by the Ras effector Rlf.

Rlf is a ubiquitously expressed distinct relative of RalGDS that interacts with active Ras in vitro. We now demonstrate that Rlf, when co-expressed with Ras mutants, associates in vivo with RasV12 and the effector-domain mutant RasV12G37, but not with RasV12E38 or RasV12C40. Rlf exhibits guanine nuc...

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Hlavní autoři: Wolthuis, R M, de Ruiter, N D, Cool, R H, Bos, J L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170279/
https://ncbi.nlm.nih.gov/pubmed/9362489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.22.6748
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