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Several cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferase.
Lysosomal targeting of soluble lysosomal hydrolases is mediated by mannose 6-phosphate receptors, which recognize and bind mannose 6-phosphate residues in the oligosaccharide chains of proteins destined for delivery to lysosomes. This recognition marker is generated by the sequential action of two e...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170273/ https://ncbi.nlm.nih.gov/pubmed/9362483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.22.6684 |
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