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Several cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferase.

Lysosomal targeting of soluble lysosomal hydrolases is mediated by mannose 6-phosphate receptors, which recognize and bind mannose 6-phosphate residues in the oligosaccharide chains of proteins destined for delivery to lysosomes. This recognition marker is generated by the sequential action of two e...

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Détails bibliographiques
Auteurs principaux: Tikkanen, R, Peltola, M, Oinonen, C, Rouvinen, J, Peltonen, L
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170273/
https://ncbi.nlm.nih.gov/pubmed/9362483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.22.6684
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