Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells.

Genomic reprogramming of primordial germ cells (PGCs), which includes genome-wide demethylation, prevents aberrant epigenetic modifications from being transmitted to subsequent generations. This process also ensures that homologous chromosomes first acquire an identical epigenetic status before an a...

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Detaylı Bibliyografya
Asıl Yazarlar: Tada, M, Tada, T, Lefebvre, L, Barton, S C, Surani, M A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170256/
https://ncbi.nlm.nih.gov/pubmed/9351832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.21.6510
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