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Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells.
Genomic reprogramming of primordial germ cells (PGCs), which includes genome-wide demethylation, prevents aberrant epigenetic modifications from being transmitted to subsequent generations. This process also ensures that homologous chromosomes first acquire an identical epigenetic status before an a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170256/ https://ncbi.nlm.nih.gov/pubmed/9351832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.21.6510 |
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