Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3.

pp72syk is essential for development and function of several hematopoietic cells, and it becomes activated through tandem SH2 interaction with ITAM motifs in immune response receptors. Since Syk is also activated through integrins, which do not contain ITAMs, a CHO cell model system was used to stud...

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Bibliografiske detaljer
Main Authors: Gao, J, Zoller, K E, Ginsberg, M H, Brugge, J S, Shattil, S J
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170248/
https://ncbi.nlm.nih.gov/pubmed/9351824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.21.6414
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