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The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast.

The budding yeast Cdc6 protein (Cdc6p) is essential for formation of pre-replicative complexes (pre-RCs) at origins of DNA replication. Regulation of pre-RC assembly plays a key role in making initiation of DNA synthesis dependent upon passage through mitosis and in limiting DNA replication to once...

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Bibliografiska uppgifter
Huvudupphovsmän: Drury, L S, Perkins, G, Diffley, J F
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170227/
https://ncbi.nlm.nih.gov/pubmed/9312054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.19.5966
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