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The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast.
The budding yeast Cdc6 protein (Cdc6p) is essential for formation of pre-replicative complexes (pre-RCs) at origins of DNA replication. Regulation of pre-RC assembly plays a key role in making initiation of DNA synthesis dependent upon passage through mitosis and in limiting DNA replication to once...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170227/ https://ncbi.nlm.nih.gov/pubmed/9312054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.19.5966 |
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