Identification and functional characterization of a second chain of the interleukin-10 receptor complex.

Interleukin-10 (IL-10) is a pleiotropic cytokine which signals through a specific cell surface receptor complex. Only one chain, that for ligand binding (IL-10Ralpha or IL-10R1), was identified previously. We report here that, although human IL-10 binds to the human IL-10R1 chain expressed in hamste...

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Main Authors: Kotenko, S V, Krause, C D, Izotova, L S, Pollack, B P, Wu, W, Pestka, S
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170220/
https://ncbi.nlm.nih.gov/pubmed/9312047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.19.5894
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