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Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis.
Cofilin stimulates actin filament turnover in vivo. The phenotypes of twenty yeast cofilin mutants generated by systematic mutagenesis were determined. Ten grew as well as the wild type and showed no cytoskeleton defects, seven were recessive-lethal and three were conditional-lethal and caused sever...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170184/ https://ncbi.nlm.nih.gov/pubmed/9312011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.18.5520 |
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