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Essential functions and actin-binding surfaces of yeast cofilin revealed by systematic mutagenesis.

Cofilin stimulates actin filament turnover in vivo. The phenotypes of twenty yeast cofilin mutants generated by systematic mutagenesis were determined. Ten grew as well as the wild type and showed no cytoskeleton defects, seven were recessive-lethal and three were conditional-lethal and caused sever...

詳細記述

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書誌詳細
主要な著者: Lappalainen, P, Fedorov, E V, Fedorov, A A, Almo, S C, Drubin, D G
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170184/
https://ncbi.nlm.nih.gov/pubmed/9312011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.18.5520
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