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Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene.
Nucleotide excision repair (NER) is a major pathway to remove pyrimidine dimers (PDs), a class of DNA lesions generated by ultraviolet light. Since folding of DNA into nucleosomes restricts its accessibility and since transcription and DNA repair require access to DNA, nucleosome structure and posit...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170139/ https://ncbi.nlm.nih.gov/pubmed/9305646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5046 |
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