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Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene.

Nucleotide excision repair (NER) is a major pathway to remove pyrimidine dimers (PDs), a class of DNA lesions generated by ultraviolet light. Since folding of DNA into nucleosomes restricts its accessibility and since transcription and DNA repair require access to DNA, nucleosome structure and posit...

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Autors principals: Wellinger, R E, Thoma, F
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170139/
https://ncbi.nlm.nih.gov/pubmed/9305646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5046
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