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A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor.

Polyadenylation is the second step in 3' end formation of most eukaryotic mRNAs. In Saccharomyces cerevisiae, this step requires three trans-acting factors: poly(A) polymerase (Pap1p), cleavage factor I (CF I) and polyadenylation factor I (PF I). Here, we describe the purification and subunit c...

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Autori principali: Preker, P J, Ohnacker, M, Minvielle-Sebastia, L, Keller, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170099/
https://ncbi.nlm.nih.gov/pubmed/9303317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.15.4727
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