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T-cell subset-specific expression of the IL-4 gene is regulated by a silencer element and STAT6.
During development of CD4+ T lymphocytes in the periphery, differential expression of cytokine genes, such as those of interleukin (IL)-2 and IL-4, occurs in distinct T-cell subsets. IL-4 is a cytokine produced by T-helper 2 (Th2) cells, and the IL-4 receptor (IL-4R)-mediated signaling pathway is th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170024/ https://ncbi.nlm.nih.gov/pubmed/9233810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.13.4007 |
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