Proteolytic processing regulates receptor specificity and activity of VEGF-C.

The recently identified vascular endothelial growth factor C (VEGF-C) belongs to the platelet-derived growth factor (PDGF)/VEGF family of growth factors and is a ligand for the endothelial-specific receptor tyrosine kinases VEGFR-3 and VEGFR-2. The VEGF homology domain spans only about one-third of...

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Detalhes bibliográficos
Main Authors: Joukov, V, Sorsa, T, Kumar, V, Jeltsch, M, Claesson-Welsh, L, Cao, Y, Saksela, O, Kalkkinen, N, Alitalo, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170014/
https://ncbi.nlm.nih.gov/pubmed/9233800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.13.3898
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