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Mechanism of TGFbeta receptor inhibition by FKBP12.
Transforming growth factor-beta (TGFbeta) signaling requires phosphorylation of the type I receptor TbetaR-I by TbetaR-II. Although TGFbeta promotes the association of TbetaR-I with TbetaR-II, these receptor components have affinity for each other which can lead to their ligand-independent activatio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170011/ https://ncbi.nlm.nih.gov/pubmed/9233797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.13.3866 |
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