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The structure of the isolated, central hairpin of the HDV antigenomic ribozyme: novel structural features and similarity of the loop in the ribozyme and free in solution.

The structure of an RNA hairpin containing a seven-nucleotide loop that is present in the self-cleaving sequence of hepatitis delta virus antigenomic RNA was determined by high resolution NMR spectroscopy. The loop, which is composed of only one purine and six pyrimidines, has a suprisingly stable s...

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Autores principales: Kolk, M H, Heus, H A, Hilbers, C W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169992/
https://ncbi.nlm.nih.gov/pubmed/9218809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.12.3685
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