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Mapping metal ions at the catalytic centres of two intron-encoded endonucleases.
Divalent metal ions play a crucial role in forming the catalytic centres of DNA endonucleases. Substitution of Mg2+ ions by Fe2+ ions in two archaeal intron-encoded homing endonucleases, I-DmoI and I-PorI, yielded functional enzymes and enabled the generation of reactive hydroxyl radicals within the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169943/ https://ncbi.nlm.nih.gov/pubmed/9214642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.3272 |
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