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Localization of Sir2p: the nucleolus as a compartment for silent information regulators.
In wild-type budding yeast strains, the proteins encoded by SIR3, SIR4 and RAP1 co-localize with telomeric DNA in a limited number of foci in interphase nuclei. Immunostaining of Sir2p shows that in addition to a punctate staining that coincides with Rap1 foci, Sir2p localizes to a subdomain of the...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169941/ https://ncbi.nlm.nih.gov/pubmed/9214640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.3243 |
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