Localization of Sir2p: the nucleolus as a compartment for silent information regulators.

In wild-type budding yeast strains, the proteins encoded by SIR3, SIR4 and RAP1 co-localize with telomeric DNA in a limited number of foci in interphase nuclei. Immunostaining of Sir2p shows that in addition to a punctate staining that coincides with Rap1 foci, Sir2p localizes to a subdomain of the...

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Main Authors: Gotta, M, Strahl-Bolsinger, S, Renauld, H, Laroche, T, Kennedy, B K, Grunstein, M, Gasser, S M
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169941/
https://ncbi.nlm.nih.gov/pubmed/9214640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.3243
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