Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.

Gene silencing is required to stably maintain distinct patterns of gene expression during eukaryotic development and has been correlated with the induction of chromatin domains that restrict gene activity. We describe the isolation of human (EZH2) and mouse (Ezh1) homologues of the Drosophila Polyco...

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Hauptverfasser: Laible, G, Wolf, A, Dorn, R, Reuter, G, Nislow, C, Lebersorger, A, Popkin, D, Pillus, L, Jenuwein, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169939/
https://ncbi.nlm.nih.gov/pubmed/9214638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.3219
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