IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.

The activity of transcription factor NFkappaB is regulated by its subcellular localization. In most cell types, NFkappaB is sequestered in the cytoplasm due to binding of the inhibitory protein IkappaB alpha. Stimulation of cells with a wide variety of agents results in degradation of IkappaB alpha...

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Bibliographic Details
Main Authors: Schouten, G J, Vertegaal, A C, Whiteside, S T, Israël, A, Toebes, M, Dorsman, J C, van der Eb, A J, Zantema, A
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169932/
https://ncbi.nlm.nih.gov/pubmed/9214631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.3133
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