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Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6.

A primer extension (toeprinting) assay was used to monitor selection by ribosomes of the first versus the second AUG codon as a function of introducing mutations on the 3' side (positions +4, +5 and +6) of the first AUG codon. Six different flanking codons starting with G (GCG, GCU, GCC, GCA, G...

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Bibliografske podrobnosti
Glavni avtor: Kozak, M
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169848/
https://ncbi.nlm.nih.gov/pubmed/9171361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2482
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