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Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6.
A primer extension (toeprinting) assay was used to monitor selection by ribosomes of the first versus the second AUG codon as a function of introducing mutations on the 3' side (positions +4, +5 and +6) of the first AUG codon. Six different flanking codons starting with G (GCG, GCU, GCC, GCA, G...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169848/ https://ncbi.nlm.nih.gov/pubmed/9171361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2482 |
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