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FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.

WW domains are conserved protein motifs of 38-40 amino acids found in a broad spectrum of proteins. They mediate protein-protein interactions by binding proline-rich modules in ligands. A 10 amino acid proline-rich portion of the morphogenic protein, formin, is bound in vitro by both the WW domain o...

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Autors principals: Bedford, M T, Chan, D C, Leder, P
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169838/
https://ncbi.nlm.nih.gov/pubmed/9171351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2376
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