Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization.

The diverse function of retinoic acid (RA) is mediated by its nuclear receptors, the retinoic acid receptors (RARs) and retinoid X receptors (RXRs). However, the RA response is often lost in cancer cells that express the receptors. Previously, it was demonstrated that the RA response is regulated by...

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Autores principales: Wu, Q, Li, Y, Liu, R, Agadir, A, Lee, M O, Liu, Y, Zhang, X
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169770/
https://ncbi.nlm.nih.gov/pubmed/9130711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1656
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